Thyroid scintigraphy differentiates subtypes of congenital hypothyroidism

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Benefits and Risks of Thyroid Scintigraphy in Congenital Primary Hypothyroidism

The diagnosis on the basis of low serum thyroxine level wiJh high thyrotropin level of congenital pri1111lfY hypothyroidism in newborn screening programs fails to distinguish between transient hypothyroidism and ectopic thyroid, athyrosis, dyshormonogenesis, or transient hyperthyrotropinemill. The correct use of neonotol thyroid scintigraphy aids in making a specific anatomic diagnosis. We scan...

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Congenital Hypothyroidism and Thyroid Cancer

Congenital hypothyroidism (CH) is a condition of thyroid hormone deficiency present at birth and can result in severe neurodevelopmental impairment, growth failure and permanent mental retardation if treatment is delayed for several months after birth (1-3). Girls are more frequently affected than boys (female to male ratios ranging from 2:1 to 4:1)(4). The mental retardation and neurodevelopme...

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Microfollicular thyroid adenoma and congenital goitrous hypothyroidism.

Three patients with congenital goitrous hypothyroidism are reported. They were treated with adequate thyroxine replacement and developed well defined microfollicular thyroid adenomas despite being euthyroid clinically and biochemically throughout their clinical course. Patients with congenital goitrous hypothyroidism appear to be at increased risk of developing thyroid adenoma in childhood desp...

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The key role of newborn thyroid scintigraphy with isotopic iodide (123I) in defining and managing congenital hypothyroidism.

BACKGROUND Thyroid imaging with isotopic iodide (123I) or technetium Tc 99m pertechnetate has been available for decades but is not routinely used in newborn infants diagnosed with congenital hypothyroidism (CH). Among clinicians who believe that presence, absence, or abnormal location of a thyroid does not alter management of CH, imaging is not advocated for anatomic diagnosis of CH. OBJECTI...

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Characteristics of thyroid nodules in infant with congenital hypothyroidism

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2019

ISSN: 0003-9888,1468-2044

DOI: 10.1136/archdischild-2019-317665